It never really seemed like the characters (save for some, like Trevor) wanted to be going on a heist. The biggest problem with Grand Theft Auto 5's heist missions was the way they were framed in the story. However, the heist missions players actually received in the game left a lot to be desired. The heist aspect of Grand Theft Auto 5 was talked up immensely before the game launched, both for its single-player mode and Grand Theft Auto Online.
If Grand Theft Auto 6 decides to bring back heist missions, hopefully they will take a page of of Grand Theft Auto: Vice City's book and make them lighthearted, enjoyable affairs.